Prodrugs - Intro, chemistry, classification, Applications
APPLICATIONS OF PRODRUGS
1. To Improve patient acceptance
3. Improvement of Odour
4. Enhancement of Bio-Availability (Lipophilicity)
5. Increased duration of action
6. To reduce gastric irritation
7. To improve chemical stability.
8. Prodrugs for increased water solubility
9. To decrease drug’s toxicity and adverse effects
10. To reduce pain at injection site
11. Protection from rapid metabolism and excretion
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