Physicochemical properties of drugs | Ionization, partion coefficient August 28, 2021 (1) Ionization (2) Partition coefficient (3) Solubility (4) Protein binding (5) Chelation (6) Bioisosterism (7) H-bonding (8) Optical and geometrical isomerism (1) Ionization - • When any drug molecule accept release the electron…
Beta Lactamase inhibitors | Unit-1 L-4 | Medicinal chemistry 6th sem June 11, 2021 BETA LACTAMASE INHIBITORS • Beta lactamase are a family of enzymes produced by many gram positive and gram negative bacteria that inactivate beta lactam antibiotics by opening the beta lactam ring. • Beta lactamase inhibitors …
